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Monday, April 30, 2012
Sunday, April 29, 2012
Origin PC joins the 11-inch, rebadged gaming laptop party, outs the EON 11-S
Last week may have drawn to a close, but the march of Clevo news continues. On the heels of Maingear announcing an 11-inch gaming notebook, Origin PC is throwing its own ultraportable into the ring: the EON 11-S. Though this is a new model for the company (the smallest laptop it's ever sold, in fact), it's not quite fresh to us: this is the same exact Clevo-made notebook Maingear unveiled two days ago, only re-badged under Origin PC's brand and available in a wider range of colors. As far as performance goes, then, that means you can expect Ivy Bridge processors, a 2GB NVIDIA GT 650M GPU, Optimus graphics-switching technology and a battery rated for 6.5 hours of runtime. In Origin PC's case, the laptop starts at $999 (compared with $1,099 for Maingear), though you'll have to head over to Origin's site for a breakdown of what specs you'll be getting at that lower price. (Spoiler alert: adding an Ivy Bridge CPU instantly bumps the price to $1,294.)
Continue reading Origin PC joins the 11-inch, rebadged gaming laptop party, outs the EON 11-S
Origin PC joins the 11-inch, rebadged gaming laptop party, outs the EON 11-S originally appeared on Engadget on Sun, 29 Apr 2012 00:01:00 EDT. Please see our terms for use of feeds.
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Origin PC joins the 11-inch, rebadged gaming laptop party, outs the EON 11-S
Last week may have drawn to a close, but the march of Clevo news continues. On the heels of Maingear announcing an 11-inch gaming notebook, Origin PC is throwing its own ultraportable into the ring: the EON 11-S. Though this is a new model for the company (the smallest laptop it's ever sold, in fact), it's not quite fresh to us: this is the same exact Clevo-made notebook Maingear unveiled two days ago, only re-badged under Origin PC's brand and available in a wider range of colors. As far as performance goes, then, that means you can expect Ivy Bridge processors, a 2GB NVIDIA GT 650M GPU, Optimus graphics-switching technology and a battery rated for 6.5 hours of runtime. In Origin PC's case, the laptop starts at $999 (compared with $1,099 for Maingear), though you'll have to head over to Origin's site for a breakdown of what specs you'll be getting at that lower price. (Spoiler alert: adding an Ivy Bridge CPU instantly bumps the price to $1,294.)
Continue reading Origin PC joins the 11-inch, rebadged gaming laptop party, outs the EON 11-S
Origin PC joins the 11-inch, rebadged gaming laptop party, outs the EON 11-S originally appeared on Engadget on Sun, 29 Apr 2012 00:01:00 EDT. Please see our terms for use of feeds.
Permalink |Origin PC | Email this | Commentspfizer signing day 2012 football gasland college football recruiting bjork national signing day 2012 landon collins
Wednesday, April 25, 2012
Ricky Gervais Is Up To His Usual Mockery In Today's Twitter-Wood
Ah, Ricky Gervais. It seems like there's not enough words to describe him, but we're also rendered speechless when we think of his antics as a two-time Golden Globe host and the star of the original "Office." Currently, Gervais is filming "Idiot Abroad" specials with producer Karl Pilkington and actor Warwick Davis, who works with [...]
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U.S. says has raised North Korea missile-linked sale with China
[ [ [['A picture is worth a thousand words', 5]], 'http://news.yahoo.com/why-facebook-bought-instagram-4-theories-160400376.html', '[Related: Why Facebook bought Instagram: 4 theories]', ' ', '630', ' ', ' ', ], [ [['He was in shock and still strapped to his seat', 9]], 'http://contributor.yahoo.com/join/yahoonews_virginiabeach', '[Did you witness the jet crash? Share your story with Yahoo! News]', ' ', '630', ' ', ' ', ], [ [['A JetBlue flight from New York to Las Vegas', 3]], 'http://yhoo.it/GV9zpj', '[Related: View photos of the JetBlue plane in Amarillo]', ' ', '630', ' ', ' ', ], [ [['Dick Clark', 11]], 'http://news.yahoo.com/photos/dick-clark-dies-at-82-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/a/p/us/news/editorial/c/21/c217c61aa2d5872244c08caa13c16ec5.jpeg', '500', ' ', 'Reuters', ], [ [['the 28-year-old neighborhood watchman who shot and killed', 15]], 'http://news.yahoo.com/photos/white-house-stays-out-of-teen-s-killing-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/cv/ip/ap/default/120411/martinzimmermen.jpg', '630', ' ', 'AP', ], [ [['Titanic', 7]], 'http://news.yahoo.com/titanic-anniversary/', ' ', 'http://l.yimg.com/a/p/us/news/editorial/b/4e/b4e5ad9f00b5dfeeec2226d53e173569.jpeg', '550', ' ', ' ', ], [ [['He was in shock and still strapped to his seat', 6]], 'http://news.yahoo.com/photos/navy-jet-crashes-in-virginia-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/cv/ip/ap/default/120406/jet_ap.jpg', '630', ' ', 'AP', ], [ [['xxxxxxxxxxxx', 11]], 'http://news.yahoo.com/photos/russian-grannies-win-bid-to-sing-at-eurovision-1331223625-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/a/p/us/news/editorial/1/56/156d92f2760dcd3e75bcd649a8b85fcf.jpeg', '500', ' ', 'AP', ] ]
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Use Internet Marketing To Help Your Business Earnings Soar - JION ...
If you are in the process of creating a business, it can be very beneficial to consider how the use of web marketing may help you. It?s highly likely that you can interact each day with a phenomenal number of individuals on the internet. There isn?t any way you can reach this number of folks with offline marketing techniques. You could reach people everywhere when you advertise on the web. You could see why this type of advertising would be better than any other form of advertising.
If you think about how expensive it can be to rent a billboard or hire telemarketers, web marketing really doesn?t cost a lot. Some web marketing methods are pricey but because many methods are actually pretty low-cost, this type of advertising is preferred by many. Generally, a typical business doesn?t have the funding for banner advertising on a top website, but many inexpensive choices are also available. One of the most favored forms of online marketing is pay-per-click-marketing through the search engines. Internet marketing works very fast and can be really effective, thus giving it an edge over other methods of marketing. End Your Tinnitus review
When you use the usual advertising methods, there?s a significant amount of lead time needed, while online you can get things moving in no time at all. It?s going to take days to get an advert in the papers, but almost immediately with an ad online. If you only look at how quick and inexpensively you can advertise with web marketing, you aren?t be saying much; the fact that it works extremely well is what makes it the best choice. Today, people generally feel confident about the legitimacy of online ads and, therefore, you have the opportunity to develop a huge database of buyers. You are wanting to connect with the most people you?re able to who are part of your target audience. You?re making use of the power of internet marketing to contact people who want the products and services you are selling. Avanti WD361 review
Through email marketing, you can contact lots of individuals anytime you want. Although you will get the best results when you send email to a list you personally created, you also have the option of paying for or renting lists. These might not work for you. When you first start marketing on the web, it is recommended by knowledgeable marketers that you promptly begin setting up an email list of your own. In order to reach a wider audience, a fantastic tool to have is your own web site. It?s crucial that you have great design and search engine optimization integration so that folks can find it on the net. Try not to overuse keywords in order to stop the search engines from banning you because of spamming. Clickertraining
Using internet marketing for site advertising can be incredibly helpful. You?ll find an abundance of ways to interact with your prospective customers around the world. It may take you a while to learn everything about online marketing, but if you have a business you want to make profitable, it is the way to go.
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Tuesday, April 24, 2012
Gatekeeper of brain steroid signals boosts emotional resilience to stress
![[ Back to EurekAlert! ]](http://www.eurekalert.org/images/back2e.gif){kind=small}
Public release date: 23-Apr-2012[ | E-mail |
Share ] Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine
PHILADELPHIA - A cellular protein called HDAC6, newly characterized as a gatekeeper of steroid biology in the brain, may provide a novel target for treating and preventing stress-linked disorders, such as depression and post-traumatic stress disorder (PTSD), according to research from the Perelman School of Medicine at the University of Pennsylvania.
Glucocorticoids are natural steroids secreted by the body during stress. A small amount of these hormones helps with normal brain function, but their excess is a precipitating factor for stress-related disorders.
Glucocorticoids exert their effects on mood by acting on receptors in the nucleus of emotionregulating neurons, such as those producing the neurotransmitter serotonin. For years, researchers have searched for ways to prevent deleterious effects of stress by blocking glucocorticoids in neurons. However, this has proved difficult to do without simultaneously interfering with other functions of these hormones, such as the regulation of immune function and energy metabolism.
In a recent Journal of Neuroscience paper, the lab of Olivier Berton, PhD, assistant professor of Psychiatry, shows how a regulator of glucocorticoid receptors may provide a path towards resilience to stress by modulating glucocorticoid signaling in the brain. The protein HDAC6, which is particularly enriched in serotonin pathways, as well as in other mood-regulatory regions in both mice and humans, is ideally distributed in the brain to mediate the effect of glucocorticoids on mood and emotions. HDAC6 likely does this by controlling the interactions between glucocorticoid receptors and hormones in these serotonin circuits.
Experiments that first alerted Berton and colleagues to a peculiar role of HDAC6 in stress adaptation came from an approach that reproduces certain clinical features of traumatic stress and depression in mice. The animals are exposed to brief bouts of aggression from trained "bully" mice. In most aggression-exposed mice this experience leads to the development of a lasting form of social aversion that can be treated by chronic administration of antidepressants.
In contrast, a portion of mice exposed to chronic aggression consistently express spontaneous resilience to the stress and do not develop any symptoms. By comparing gene expression in the brains of spontaneously resilient and vulnerable mice, Berton and colleagues discovered that reducing HDAC6 expression is a hallmark of naturally resilient animals. While aggression also caused severe changes in the shape of serotonin neurons and their capacity to transmit electrical signals in vulnerable mice, stress-resilient mice, in contrast, escaped most of these neurobiological changes.
To better understand the link between HDAC6 and the development of stress resilience, Berton and colleagues devised a genetic approach to directly manipulate HDAC6 levels in neurons: Deletion of HDAC6 in serotonin neurons -- the densest HDAC6-expressing cell group in the mouse brain -- dramatically reduced social and anxiety symptoms in mice exposed to bullies and also fully prevented neurobiological changes due to stress, fully mimicking a resilient phenotype.
Using biochemical assays, Berton's team showed it is by promoting reversible chemical changes onto a heat shock chaperone protein, Hsp90, that HDAC6 deletion is able to literally switch off the effects of glucocorticoid hormones on social and anxiety behaviors.
Chaperones are proteins that help with the folding or unfolding and the assembly or disassembly of protein complexes. The way in which glucocorticoid receptor chaperoning and stress are linked is not well understood. Yet, genetic variations in certain components of the glucocorticoid receptor chaperone complex have been associated with the development of stress-related disorders and individual variability in therapeutic responses to antidepressants.
"We provide pharmacological and genetic evidence indicating that HDAC6 controls certain aspects of Hsp90 structure and function in the brain, and thereby modulates protein interactions, as well as hormone- and stress-induced glucocorticoid receptor signaling and behavior," explains Berton.
Together, these results identify HDAC6 as a possible stress vulnerability biomarker and point to pharmacological inhibition of HDAC6 as a potential new strategy for antidepressant interventions through regulation of Hsp90 in glucocorticoid signaling in serotonin neurons.
###
Co-first-authors are Julie Espallergues and Sarah L. Teegarden, along with Avin Veerakumar, Janette Boulden, Collin Challis, Jeanine Jochems, Michael Chan, Tess Petersen, Chang-Gyu Hahn, Irwin Lucki, and Sheryl G. Beck, all from Penn. Other authors are Evan Deneris, from Case Western Reserve University, Cleveland, Ohio, and Patrick Matthias, Miescher Institute for Biomedical Research, Basel, Switzerland.
This work was funded by the National Institute of Mental Health grants MH087581 and MH0754047 and grants from the International Mental Health Research Organization and the National Alliance for Research on Schizophrenia and Depression.
Penn Medicine is one of the world's leading academic medical centers, dedicated to the related missions of medical education, biomedical research, and excellence in patient care. Penn Medicine consists of the Raymond and Ruth Perelman School of Medicine at the University of Pennsylvania (founded in 1765 as the nation's first medical school) and the University of Pennsylvania Health System, which together form a $4.3 billion enterprise.
The Perelman School of Medicine is currently ranked #2 in U.S. News & World Report's survey of research-oriented medical schools. The School is consistently among the nation's top recipients of funding from the National Institutes of Health, with $479.3 million awarded in the 2011 fiscal year.
The University of Pennsylvania Health System's patient care facilities include: The Hospital of the University of Pennsylvania -- recognized as one of the nation's top 10 hospitals by U.S. News & World Report; Penn Presbyterian Medical Center; and Pennsylvania Hospital - the nation's first hospital, founded in 1751. Penn Medicine also includes additional patient care facilities and services throughout the Philadelphia region.
Penn Medicine is committed to improving lives and health through a variety of community-based programs and activities. In fiscal year 2011, Penn Medicine provided $854 million to benefit our community.
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Public release date: 23-Apr-2012[ | E-mail |
Share ] Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine
PHILADELPHIA - A cellular protein called HDAC6, newly characterized as a gatekeeper of steroid biology in the brain, may provide a novel target for treating and preventing stress-linked disorders, such as depression and post-traumatic stress disorder (PTSD), according to research from the Perelman School of Medicine at the University of Pennsylvania.
Glucocorticoids are natural steroids secreted by the body during stress. A small amount of these hormones helps with normal brain function, but their excess is a precipitating factor for stress-related disorders.
Glucocorticoids exert their effects on mood by acting on receptors in the nucleus of emotionregulating neurons, such as those producing the neurotransmitter serotonin. For years, researchers have searched for ways to prevent deleterious effects of stress by blocking glucocorticoids in neurons. However, this has proved difficult to do without simultaneously interfering with other functions of these hormones, such as the regulation of immune function and energy metabolism.
In a recent Journal of Neuroscience paper, the lab of Olivier Berton, PhD, assistant professor of Psychiatry, shows how a regulator of glucocorticoid receptors may provide a path towards resilience to stress by modulating glucocorticoid signaling in the brain. The protein HDAC6, which is particularly enriched in serotonin pathways, as well as in other mood-regulatory regions in both mice and humans, is ideally distributed in the brain to mediate the effect of glucocorticoids on mood and emotions. HDAC6 likely does this by controlling the interactions between glucocorticoid receptors and hormones in these serotonin circuits.
Experiments that first alerted Berton and colleagues to a peculiar role of HDAC6 in stress adaptation came from an approach that reproduces certain clinical features of traumatic stress and depression in mice. The animals are exposed to brief bouts of aggression from trained "bully" mice. In most aggression-exposed mice this experience leads to the development of a lasting form of social aversion that can be treated by chronic administration of antidepressants.
In contrast, a portion of mice exposed to chronic aggression consistently express spontaneous resilience to the stress and do not develop any symptoms. By comparing gene expression in the brains of spontaneously resilient and vulnerable mice, Berton and colleagues discovered that reducing HDAC6 expression is a hallmark of naturally resilient animals. While aggression also caused severe changes in the shape of serotonin neurons and their capacity to transmit electrical signals in vulnerable mice, stress-resilient mice, in contrast, escaped most of these neurobiological changes.
To better understand the link between HDAC6 and the development of stress resilience, Berton and colleagues devised a genetic approach to directly manipulate HDAC6 levels in neurons: Deletion of HDAC6 in serotonin neurons -- the densest HDAC6-expressing cell group in the mouse brain -- dramatically reduced social and anxiety symptoms in mice exposed to bullies and also fully prevented neurobiological changes due to stress, fully mimicking a resilient phenotype.
Using biochemical assays, Berton's team showed it is by promoting reversible chemical changes onto a heat shock chaperone protein, Hsp90, that HDAC6 deletion is able to literally switch off the effects of glucocorticoid hormones on social and anxiety behaviors.
Chaperones are proteins that help with the folding or unfolding and the assembly or disassembly of protein complexes. The way in which glucocorticoid receptor chaperoning and stress are linked is not well understood. Yet, genetic variations in certain components of the glucocorticoid receptor chaperone complex have been associated with the development of stress-related disorders and individual variability in therapeutic responses to antidepressants.
"We provide pharmacological and genetic evidence indicating that HDAC6 controls certain aspects of Hsp90 structure and function in the brain, and thereby modulates protein interactions, as well as hormone- and stress-induced glucocorticoid receptor signaling and behavior," explains Berton.
Together, these results identify HDAC6 as a possible stress vulnerability biomarker and point to pharmacological inhibition of HDAC6 as a potential new strategy for antidepressant interventions through regulation of Hsp90 in glucocorticoid signaling in serotonin neurons.
###
Co-first-authors are Julie Espallergues and Sarah L. Teegarden, along with Avin Veerakumar, Janette Boulden, Collin Challis, Jeanine Jochems, Michael Chan, Tess Petersen, Chang-Gyu Hahn, Irwin Lucki, and Sheryl G. Beck, all from Penn. Other authors are Evan Deneris, from Case Western Reserve University, Cleveland, Ohio, and Patrick Matthias, Miescher Institute for Biomedical Research, Basel, Switzerland.
This work was funded by the National Institute of Mental Health grants MH087581 and MH0754047 and grants from the International Mental Health Research Organization and the National Alliance for Research on Schizophrenia and Depression.
Penn Medicine is one of the world's leading academic medical centers, dedicated to the related missions of medical education, biomedical research, and excellence in patient care. Penn Medicine consists of the Raymond and Ruth Perelman School of Medicine at the University of Pennsylvania (founded in 1765 as the nation's first medical school) and the University of Pennsylvania Health System, which together form a $4.3 billion enterprise.
The Perelman School of Medicine is currently ranked #2 in U.S. News & World Report's survey of research-oriented medical schools. The School is consistently among the nation's top recipients of funding from the National Institutes of Health, with $479.3 million awarded in the 2011 fiscal year.
The University of Pennsylvania Health System's patient care facilities include: The Hospital of the University of Pennsylvania -- recognized as one of the nation's top 10 hospitals by U.S. News & World Report; Penn Presbyterian Medical Center; and Pennsylvania Hospital - the nation's first hospital, founded in 1751. Penn Medicine also includes additional patient care facilities and services throughout the Philadelphia region.
Penn Medicine is committed to improving lives and health through a variety of community-based programs and activities. In fiscal year 2011, Penn Medicine provided $854 million to benefit our community.
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
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Latest health articles - HEALTH, BEAUTY & FITNESS
The risk of high bloodstream pressure or possibly heart disease in males is continuing to grow to really dangerous levels in the united states . Based on AP, People in america Wish to Tax Wealthy to cover Health care Something for free is, apparently, the attitude during the day in the usa, or at best among individuals who arent ? wealthy.? A current AP poll established that most People in america want the Federal government latest to tax the nations wealthy to be able to cover the huge cost which will come together with health care reform. Difficulty: Moderately Easy Instructions 1) Prepare the needed documents that prove your Canadian citizenship or immigration status. Individuals with the greater serious health conditions which are more severe simply because they just could not afford maintenance previously, as well as the administrative ineffectiveness waste has affected the American healthcare system with greater cost and it is draining the economy before our very eyes. This could include new techniques of testing, studies or health festivals. However, black tea still offers many positive health advantages, and Darjeeling teas are frequently known as the ? champagne of black tea.? Health Benefit Studies Several research has been done health on the health advantages of black tea. There? s additionally a national pool for citizens of states that not participate. 3) Outline the methods and services that you? ll provide inside your service. Medicare insurance tri city health center serves people 65 or older, people under age 65 with certain disabilities, the ones of any age with Finish- Stage Kidney Disease ( permanent kidney failure needing dialysis or perhaps a kidney transplant), based on the latest health articles U. S. Be conscious from the specific issues facing agencies in a few regions. It will begin most abundant in recent one. The whole room ought to be lighted, not only the significant area. Various facets of health care, for example Significant Use, city Patient Protection and Affordable Care Act of 2010, HIPAA, HITECH Act, Stark and Anti Kickback Act, Valid Consent, Patient Safety and Process Improvement, Patient Safety and Quality Final results, Health care It Standards Panel ( HITSP), articles Drug Abuse and Mental Health Records, Nursing Informatics, Health health care Disclosure, Electronic Transactions Standards for example 5010 and ICD- 10, Electronic Health Records, Stimulus Code, Health care Information Exchange, Health care It, Medical Necessity, Personal Health tri Records, Clinical Decision Support, Financial Management and Return on investment, Electronic Prescribing, Health center care Information Systems, Clinical Informatics, Claim Appeals, Auto ID and Bar Coding, Integration and Interoperability, Risk Management within the latest health articles Retention and Destruction of Medical Records and Medical Records Law, to title only a couple of, are covered. You ought to preserve good dental health by practicing regular dental hygiene habits and going to dental professional regularly.
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Monday, April 23, 2012
Real-Time Research: iOS Dominates Over Android When It Comes To Usage, Says Chitika
Android, by most accounts, is proving to be the most popular smartphone platform when it comes to devices getting sold today -- partly due to the sheer variety of devices and price points that are out there. But a new research tool that tracks usage in real-time shows that when it comes to usage, consumers, in the U.S. at least, are far more active on Apple's devices than on any other. The numbers come from the ad network Chitika, which notes that in the last 24 hours, iOS devices, covering the iPhone, iPad and iPod models, accounted for just under 68 percent of all usage on its network. Android, meanwhile, accounted for just under 28 percent. And other platforms were less than five percent of all activity. But there have been periods in the last few days when Android accounted for as little as 19 percent of traffic (on April 19, as it happens).valentines day westminster dog show valentines day cards hallmark grammy winners obama budget woolly mammoth
Sunday, April 22, 2012
Fenway Park: Living link to baseball's past turns 100
Fenway Park has survived because it is beloved by Boston's fans and because the team owners had a vision for making improvements that have allowed the park to keep functioning, flaws and all.
Fenway Park isn't just the storied home of the Boston Red Sox. It's also a venue, perhaps more than any other ballpark now in use, that links the nation to baseball's history.
Skip to next paragraphSure, the Baseball Hall of Fame in Cooperstown, N.Y., serves as a kind of pantheon of the sport's legend and lore.
But Fenway Park ? which celebrates its first 100 years Friday ? is the sport's living shrine.
It's not that Fenway can claim to be what Wimbledon is to tennis ? the perennial home of epic events in the sport. But as the oldest major-league ball field still in use, it offers the nearest connection that today's fans can find to an earlier era when every game was played in daylight, when the telegraph defined high-tech communication, and when starting pitchers routinely pitched a full nine innings.
And it's not just that the park is old. It's also distinctive, known most of all for that giant "Green Monster" wall that dwarfs those who play left field. It's also home to a team that has captured an outsize share of affection in the hearts of fans beyond Boston.
The Sox have a story woven with themes that resonate widely for the sport's fans: hope (think Carlton Fisk's 12th-inning home run in the 1975 World Series), heartbreak (recall all those decades of championship drought) and flamboyant characters (Babe Ruth, Luis Tiant, and Jonathan Papelbon, to name a few).
So, even though most other historic ballparks were torn down long ago, Fenway has survived.
It's survived because the park is beloved by Boston's passionate fans and because the current team owners had a vision for making improvements that have allowed the park to keep functioning, flaws and all.
The celebrations Friday coincide with a game between the Sox and the New York Yankees, longtime archrivals in the American League's eastern division.
It was the sale of Sox star Ruth to the Yankees, in 1920, that prompted the long-running talk of a "curse" on Boston. The Yanks began their chain of World Series wins under Ruth, and the stadium where they played for decades was deservedly known as the "House That Ruth Built."
But that "house" in New York City is now gone. Fenway Park lives on.
The other classic major-league ballpark still in use is Wrigley Field, home of the Chicago Cubs, which opened in 1914. Wrigley can tell its own tales of hope, loss, and devoted fans. But those stories don't tend to have the intensity that Boston has provided over the years with its down-to-the-wire pennant races and recent World Series wins.
So, in a tribute to Fenway's 100th anniversary, here are some highlights of the Sox and their ballpark:
? Fenway Park's first game actually came on April 9, 1912, but it was an exhibition between the Red Sox and Harvard College. Eleven days later came the major-league opener against the New York Highlanders (now known as, yes, the Yankees). In a foretaste of thrills to come, the Sox won that game 7-6 in 11 innings.
? John F. Kennedy's grandfather, Boston Mayor John Fitzgerald, threw the ceremonial first pitch on April 20, 1912.
? In 1912, the Sox won 105 regular season games, the American League pennant, and the World Series. The team's other World Series titles while residing at Fenway came in 1915, 1916, 1918, 2004, and 2007.
? Along with the Green Monster wall, notable features of the park include "the triangle" (an angular oddity in center field where balls can ricochet) and foul poles named after Sox greats Johnny Pesky (the right-field pole) and Fisk (the left-field pole).
? Despite the long drought in World Series wins, the Sox story between 1918 and 2004 was far from dull. It included trips to the World Series in 1946, 1967, 1975, and 1986. The championship aspirations were spoiled by the St. Louis Cardinals (with a "mad dash" by Enos Slaughter coming home from first base), the Cardinals again (led by the overpowering arm of Bob Gibson), the Cincinnati Reds' "Big Red Machine," and the New York Mets (after a ground ball infamously slipped past Sox first baseman Bill Buckner to force a Game 7). Some of those moments occurred outside Fenway Park, but others, like Fisk's home run, are forever etched in the memories of Boston fans.
? In October 1978, Bucky Dent shocked Boston by hitting a home run over the Green Monster, allowing the Yankees to edge out the Sox in a crucial division playoff game at the end of the season.
?
? A turnabout moment came in 2004, when the Sox and Yanks faced each other in the American League Championship Series. The Sox appeared poised to lose in four straight games, when Kevin Millar drew a bottom-of-the-ninth walk, pinch runner Dave Roberts stole second base, and Bill Mueller drove him home with a single. The Sox went on to win the ALCS and then took their first World Series in 86 years.
? As befits its place in the sport's lore, Fenway served as a mecca for Kevin Costner and James Earl Jones in the baseball film "Field of Dreams."
? The park very nearly didn't survive. For years, team owners and local politicians grappled with questions about the field's future. Boston Globe sportswriter Bob Ryan, commenting on TV before the celebration, said the team might easily be playing now in a "theme park" field modeled on Fenway, but thanks to a few fateful decisions, "we have the real thing."
? As old as Fenway is, not all Boston's great baseball moments came with that as the home field. Pitcher Cy Young threw the first pitch at Huntington Avenue Baseball Grounds in the modern World Series in 1903 while leading the Boston Americans to a championship. The Americans became the Red Sox in 1908.
The celebration Tuesday brought a legion of former Sox players onto the field before cheering Boston fans. Among them were Jim Rice, Dwight Evans, Jim Lonborg, Pedro Martinez, Nomar Garciaparra, Dennis Eckersley, Buckner, Tiant, and Fisk. And the man who led the team back to national prominence starting in the 1960s: Carl Yastrzemski.
Then, with the former greats congregating on the field, composer John Williams unleashed a "Fanfare for Fenway."
Where once Bostonians talked of a "curse," on this day it may feel more accurate to borrow a line from Shakespeare and call Fenway a "blessed plot" of turf, brick, and bleachers that could thrive for years to come.
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Brand-To-Fan Platform Crowdtap Expands To Facebook & Mobile, Sees Revenue Soar
Crowdtap, a web-based network that allows brands to connect with their most engaged fans and customers through social media, has just expanded to two more platforms: Facebook and mobile. The mobile application comes in the form of an iPhone app which allows fans to participate in the brand's "challenges" (games and contests) in order to earn rewards. Meanwhile, the new Facebook tab sets up a special "VIP" section right on the brand's own Facebook page, to allow for interactions with its top fans.alec baldwin kicked off plane alec baldwin kicked off plane mumia mumia uss arizona memorial uss arizona memorial d day
Saturday, April 21, 2012
Nokia releases a commercial shot entirely with the 808 PureView (video)
Nokia's released a new commercial that it says is shot entirely using an 808 PureView. Whilst it's clear the company's hired a coterie of models, professional photographers and a world-class lighting rig, it's still a great indication of what the technology can do in the right hands. Head on past the break to see the results for yourself and then catch yourself seriously weighing up buying a Symbian phone for your next handset, just like we are.
Continue reading Nokia releases a commercial shot entirely with the 808 PureView (video)
Nokia releases a commercial shot entirely with the 808 PureView (video) originally appeared on Engadget on Fri, 20 Apr 2012 07:41:00 EDT. Please see our terms for use of feeds.
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This Leading Personal Injury Lawyer Barrie ... - Info PNC Legal Blog
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Financial help please | Personal Loan
I recently started a new job and will be making decent money so I am thinking of buying a home because i hate paying rent. The problem is I have already accumulated 25000 worth of debt due to credit cards and student loans. Ideally I would like to get enough money for a home loan to pay for the house and my debt. I was also considering going ahead and applying for a personal loan to at least partially pay on the 25000 to try and start reducing how much I pay in interest in case i dont get a home soon. I will also be recieving 12000 in a couple months as a gift and i need to know the best way to use this money.
Thanks ahead of time for any input.
Basic things about Financial help please
Finance
Networks of financial businesses exist to create, negotiate, market, and trade in. Help; About Wikipedia; Community portal; Recent changes; Contact Wikipedia2008?2012 global financial crisis
However, AIG did not have the financial strength to support its many CDS commitments as the crisis progressed and was taken over by the government in September 2008.Income statement
Income statements should help investors and creditors determine the past financial performance of the. Please note the difference between IFRS and US GAAP when.Financial adviser
These terms are typically selected by individuals to help describe the nature of their financial practice. The Chartered Financial Analyst (CFA) designation, the Certified.Alimony
Alimony (also called maintenance (Britain) and spousal support (U.S.)) is a U.S. term denoting a legal obligation to provide financial support to one?s spouse from.
Your home buying will not get far with the cc debt. You need to be debt free except maybe the student loans AND have a down payment AND have a backup house fixing up fund. You cannot borrow over the value of the house to pay off your other debt. Will never happen. Also do not think you can get a personal loan given your debt and lack of job history at least on your new job the bank wants to know you will be keeping it in the future. Depending on the factors in your life you might want to apply a large amount 8 9 of that 12000 to the credit card debt with the highest interest rate.
Debt charging 6 or less can be managed over a longer period of time although be making more than the minimum payments. Pay off debt before building up savings too much. No since in earning 1 taxable while paying 6 no tax break on debt. Give yourself a few years to align your finances.
Explaining financial leverage in the context of real estate investment Disclaimer None of this is meant to be personalized financial advice. Please consult a financial adviser to help with your financial decisions. For similar videos please visit.
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My dog will no longer jump she doenst play anymore and she pisses like a hose and its always got little drops of blood in ti. Does this mean she has a urinary infection.
It may or may not have anything to do with her urinary tract. She could have injured herself internally. Please take her to a vet and have her examined. If money is an issue many communities have low cost vet service. Many regular vets will do a free examination. There is financial help for you if you need it see link. But your pet depends solely on you for help. Please seek help for her she is obviously in pain and money is no excuse. Good luck.
Im actually interesting in Direct MerchandisingDistributor but I want a mentor who can help guide me in starting. HelpThanks ahead of time.
A mentor is the key to success in a distributorship business. Self development is also key. Some of my favorite leadership authors who I feel have mentored me through their writings include John Maxwell and Dr. Tom Barrett. Excellent reads. Arbonne International is commonly referred to as a personal development company disguised as a health and wellness company. I have mentors available to me in my direct upline and at the corporate office. There are lots of websites and interactive conference calls that my company offers to assist me as well.
We are currently operating in the Canada and Australia. We have opened up the United Kingdom market this month. Its an exciting time to be with such a phenomenal company. Whether you are looking for a parttime or fulltime home business Arbonne is an excellent vehicle to help you achieve financial peace. Please message or email me if you are interested in a free information packet on the Arbonne business opportunity.
Im doing a research paper for school and my topic is about the expensiveness of college and I want to know how current students and recent graduates are paying for it.
Good topic Here is all the information that I have hopefully it will help you. I was lucky that my school was cheap compare to other school in the country. I depended on parents and financial aid grants loans and scholarshipsFINANCIAL HELPI got financial aid that includes gov. Grants scholarships and school loans. The problem with financial aid is you have to claim that you are a low income. If you live with parents and they make a little more money than lowincome people then you will depend on school loans for school.
Scholarships are great but they are hard to get unless you are an athlete. Its almost like a poor person that is begging for money. So scholarship counselors dont treat applicants the best way. I graduated 2years ago and I still owe 18000 for my school. I know that is doesnt sound like a lot compare to others. I am paying back now. Not to mention every time I get in an argument with mom I still hear I paid for your school bla bla bla even though I graduate it. GOING TO SCHOOLAnyway. Although my school was not expensive like other school but there was at least a 20 increase in tuition and fees every semester.
Required to pay for the student health fees around 50 a semester and it doesnt matter if you dont use it you have to pay for it anyway. BOOKSBook are expensive you can buy a book for 60 and sells it in the end of the semester for 20 which I think it is ridicules. Some instructors DONT use the books in class but they cant say that so they dont loose their jobs. And publishers make their money from books that student dont read. It was tough being a student get financial aid and maintain a decent paying job during school.
Fot instance servers and bartenders make more money then school teachers in the state that I live in. So it is tough. I really like your topic you have a lot to talk right about I hope this information helps you with your research. Please contact if you have any questions. Good Luck.
Financial Mess. Please help
First post I apologize if I am breaking any etiquette here but I need some help.Wife and I both I need a more precise budget to help you make a ton of money and theres got to be something missingto haul yourselves around. It would help a lot to sell the cars and pay cash for affordable used cars .
I need a more precise budget to help you make a ton of money and theres got to be something missing to haul yourselves around. It would help a lot to sell the cars and pay cash for affordable used cars 8000yr. So 16000yr to .
Tips for financial advisor interviews. ? Financial Advisor
Why are you interested in becoming a financial advisor and why would you make a good onenader in Los Angeles California said why are you interested in becoming a financial advisorcant be serious with a brain dead response like that. Please dont play with anyones money. Ever .
Nader in Los Angeles California said why are you interested in becoming a financial advisor cant be serious with a brain dead response like that. Please dont play with anyones money. Ever. 12 No A better response would be to .
Please pray for us to get through the financial mess I?ve made?
Ive ruined me and my partner financially because of a terrible gambling problem. Please prayfor us to help me find the opportunities and chance through hard work and penance to remedyof a terrible gambling problem. Please pray for us to help me find the opportunities and chance .
Of a terrible gambling problem. Please pray for us to help me find the opportunities and chanceQuoteIve ruined me and my partner financially because of a terrible gambling problem. Please pray for us to help .
Financial Help
Can anyone give me any advice on how to get out of the financial trouble Im in at the moment. Thanks for reading and hopefully I can get some help.ThxPackjoker Proud manager of Glasgow Huskiesto be paying anyone 11Kpw for D45 if in financial trouble. Former UAE NT U19 Manager. Visit our .
To be paying anyone 11Kpw for D45 if in financial trouble. Former UAE NT U19 Manager. Visit our definitely dont need to be paying anyone 11Kpw for D45 if in financial trouble.I understand for D45 if in financial .
Clicky Poll: Windfalls / Significant Family Financial Help
help but minimize any significant help we have received.So for the question please consider Have you received significant financial assistance from your family or a major unearnedfinancial help although Im sure if we were in a dire situation our families would be able to come .
financial help although Im sure if we were in a dire situation our families would be able to come privilege than the average American.ETA And I dont think that I minimize help Ive received from my own since we turned 18. .
Help with Link financial and ccj forms
Hi I intend to defend the whole claim due to non receipt of letters etc would appreciate some helpgive us the full story please.Ill move your thread to the correct forum Thread moved to Legalissues Please do provide full details.Nonreceipt of letters is not really a basis to defend the claim .
Give us the full story please.Ill move your thread to the correct forum Thread moved to Legal issues Please do provide full details.Nonreceipt of letters is not really a basis to defend the claim the Limitations Act 1980.Have you .
?Please help? ?Please help?
Girlfriend which currently require financial assistance a person close to me. Please readis not the first time Please help Dear good people The letter writing to you all with a human for this. I hope and pray that you find a job that will help you relieve your financial problems. If you .
On this. I hope and pray that you find a job that will help you relieve your financial problems. If you do FeeFi Foanna and I have been engaged to send you your inheritance. Please reply with your full name .
4.0 gpa and struggling with financial aid. Advice please!
School before. Please help. I could really use some advice on what I should do. At this point I amthe financial aid and scholarships necessary for me to live on campus. And I cannot handle the stressto rethink their financial plans. What was your SAT breakdown and your ACT if you have one.OSU doesnt .
To rethink their financial plans. What was your SAT breakdown and your ACT if you have one.OSU doesnt meet need. Im sorry no one told you that.Are you a national merit finalist If so I can help youDid I have the wrong idea .
Outside Financial Help
Parents were the main financial contributors with the brides paying for the dress only.If you have anystories bad or good please share proud to be marrying my bestest friend everthe day ourselves so we didnt ask for help.We didnt have an engagement party so it doesnt really .
The day ourselves so we didnt ask for help.We didnt have an engagement party so it doesnt really no help as FH and I have paid for everything ourselves and havent asked for or had any help offered I certainly didnt .
Question about Oxford?s Financial help
Question about Oxfords Financial help HeyI am a non EU student and have got an offer for an Mscfor financial aid.I would be grateful if someone could list the options I face is there anything Question about Oxfords Financial help Quote Can I clarify something please The only MSc .
Question about Oxfords Financial help Quote Can I clarify something please The only MScRe Question about Oxfords Financial help bump Re Question about Oxfords Financial help the university ? .
Understanding What Financial Help You Need
This Element is an excerpt from Who Can You Trust With Your Money? Get the Help You Need Now and Avoid Dishonest Advisors (9780137033652) by Bonnie Kirchner. Available in print and digital formats. The components of an integrated financial plan?and how to start putting them together. Like doctors, there are many different types of financial advisors out there.
The Beatles
Please Please Me maintained the top position on the Record Retailer chart for thirty weeks, only to Beatles for Sale, Help! : and Rubber Soul .
Michael DeBatt
Michael and daughter Rosanna under financial strain and heavily indebted. approached Sammy Gravano and pleaded with him, ?Sammy, please help us.? .
OutHistory
OutHistory is designed to help us ask and begin to answer questions If you can help, please go to the Donate section of the site. .
Glass?Steagall Act
Steagall Act was an important cause of the late-2000s financial crisis . convert into bank holding companies) helped mitigate the financial crisis. .
Cornell University
Its President announced that the financial aid initiative will html title State budget pleases CU administrators last Ramanujan first .
Hello Kitty
Financial: As of 2009, Bank of America The hospital?s owner explained that he hoped that the theme would help ease the stress of childbirth .
Pink Floyd
Diverse array of social connections helped gain the band important Financial problems: Gilmour and Wright released their debut solo albums .
American International Group
2009 had increased the potential financial support to AIG, with the third party debt to help repay some of the money owed to the U.S. government .
Peter Currie
Peter L. S. Currie is a business executive notable for being the chief financial References: Stanley please? FINANCE: Peter Currie?s .
Jasenovac concentration camp
Inmate help: with the help The local representative, Julius Schmidllin, was contacted by the Jewish community, which sought financial aid. .
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Inpatient Treatment for Substance Abuse Offer Quick Recoveries
The medical practitioners in the rehab centers find it too hard to make understand the adolescent. The therapist find addressing an adolescent's is the much struggle factor when the substance abuse therapies are used for the understanding emotional, developmental, physical, psychological, familial, social and cultural factors pushed the patients for addiction. The medical rehab centers have developed inpatient substance abuse and followed the inpatient treatment for substance abuse treatment as the evidence-based along with the 12 Step-based programs to eradicate incorporates clinical, medical, educational and experiential therapies by improving the and decreasing the addiction plan.
The counselors and the medical therapist offer great scenarios to the patients between 16 or 17 years old occupied in the addiction. The counseling is provided round-the-clock and first 20 initial minutes are always provided for free.
The 24 hour nursing care and the evidence based techniques help to recognize the patient their mental conditions and addictions urges.The medical resources that are occupied such as doctors, counselors, medical representatives have been veteran and known specialists in the industry. The extensive experience and medical practitioners provided for the alcohol and drug rehab centers have made the rehab centers much more effective. The effective treatment provided on evidence-based solutions, and medicines through the inpatient treatment for substance abuse and addiction.
This helps the addicted person to find the contemporary solutions without much tedious medical therapies. These therapies are trusted easily by the adult people due to witnessing other cure people from all types of addiction in less time. When the treatments are accepted with pleasure then the effect of the therapies get doubled for recoveries. The rehab centers mainly work on two modes, physical therapies and mental therapies. There are numerous methods that bring the physical fitness and the evidence based method help to boost the patient recovery chances.
Also the substance based theories such as inpatient treatment for substance abuse. With the passing time it has been noticed by the medical institutes providing rehab centers that substance abuse education, intervention and counseling works efficiently then any other treatment. Patients find their moral boost to the highest where they fight back for the addiction themselves.
Therefore, inpatient treatment for substance abuse when merged with the evidence treatment therapies and evidence based medicines for the patients. Quick recoveries are completely based on the therapies mentioned above. So, patients need help can opt for the 24 hours a day, seven days a week open rehab centers in the country.
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Friday, April 20, 2012
This Philips Wake-Up Light Is Your The-Dawn-Is-Your-Pawn Deal of the Day [Dealzmodo]
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